Komboglyze (Saxagliptin/Metformin)

Komboglyze Information:

Buy Komboglyze

Komboglyze (Saxagliptin/Metformin) is used in combination with other therapies, such as diet and exercise, to improve blood sugar control in adults with type 2 diabetes. It is typically used when lifestyle modifications such as optimized diet, exercise, and weight reduction are not enough to control blood sugar. It contains two active ingredients: saxagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, and metformin, a biguanide. Saxagliptin works by increasing incretin hormones, which boost insulin release and decrease glucagon levels, thus lowering blood sugar. Metformin decreases glucose production in the liver and improves insulin sensitivity.

Generic Komboglyze from Canada

Canada Drugs Online proudly serves you the brand Komboglyze, manufactured by AstraZeneca from Canada. The generic Komboglyze is currently not available. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Diabetic medications and products, such as Actos.

Komboglyze Side Effects:

Common mild side effects of this medication include abdominal bloating, diarrhea, headache, heartburn, indigestion, loss of appetite, metallic taste in mouth, and nausea. Contact your doctor if these mild side effects persist or worsen.

Komboglyze may cause some serious side effects such as severe joint pain, fast, irregular heartbeat or pulse, chest pain, sudden weight gain, difficulty breathing, leg swelling, unexplained muscle pain, tenderness or weakness, or brown or discolored urine, frequent urge to urinate, pain or burning sensations when urinating, cough, fever, headache, runny nose, vision changes, hunger, headache, mood swings, slurred speech, fainting, persistent nausea and vomiting, abdominal pain, severe body itching, and rash, swelling of your face, lips, tongue, or throat, and extreme dizziness. Stop using this device and seek immediate medical attention if you notice these severe side effects. Also, inform your doctor about other side effects you see that are not listed here.

Komboglyze is effective and generally well-tolerated in clinical studies. In trials, adding saxagliptin to metformin significantly improved glycemic control compared to placebo. Everyday adverse events included headaches, upper respiratory tract infections, and gastrointestinal issues. Still, no significant differences in safety were observed between older and younger patients (source).

Komboglyze Directions:

Komboglyze tablets should be taken orally, preferably with a meal, to reduce the gastrointestinal side effects associated with metformin. Your doctor will determine the appropriate dose of this medication for you, depending on your condition and response to treatment. Take this medication regularly as prescribed by your doctor. Check out the leaflet in the medication pack for more instructions on usage. Do not use more than the prescribed dose of this medication, as it can lead to adverse effects. Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Komboglyze Precautions:

Before taking this medication, it is essential to inform your doctor about any previous or current medical conditions you may have, especially the following:
• Allergic reaction to saxagliptin, metformin, other ingredients of this medication, or any other medications;
• Dehydration;
• Heart disease such as heart failure;
• Hyperglycemic emergency such as diabetic ketoacidosis;
• Kidney disease;
• Lactic acidosis (too much acid in the blood);
• Liver disease;
• Pancreas disease such as pancreatitis;
• Vitamin B12 deficiency;
• Weak immune system

Avoid the intake of alcohol and alcoholic beverages while taking this medication, as it may increase the risk of severe side effects. Talk to your doctor before using this medication if you are experiencing or recovering from severe infections, trauma, or surgery. Monitor your blood sugar regularly at intervals as discussed with your doctor to prevent dangerously low blood sugar. Pregnant women should not use this medication. Consult your doctor before taking this medication while breastfeeding. This medication is not suitable for use in children. Some other medications may interact with Komboglyze, increasing the risk of developing side effects. Some of these medications include:
• Antifungals such as itraconazole, ketoconazole, voriconazole;
• Beta-2-agonists such as salbutamol, indacaterol, salmeterol;
• Corticosteroids such as budesonide, ciclesonide, fluticasone

Therefore, before using this medication, inform your doctor about any other medications you are currently taking, including herbal medicines and supplements, to determine if it is safe to use along with this Komboglyze.