Myfembree (Relugolix/Estradiol/Norethindrone Acetate)

Myfembree Information:

Buy Myfembree

Myfembree (Relugolix/Estradiol/Norethindrone Acetate) is used to treat heavy menstrual bleeding caused by uterine fibroids in premenopausal women. Additionally, it is used to treat moderate to severe pain stemming from endometriosis in premenopausal women. Myfembree is a combination medication containing three active ingredients: relugolix, estradiol, and norethindrone acetate. It belongs to the class of drugs known as gonadotropin-releasing hormone (GnRH) antagonists. It works by reducing the production of specific hormones like estrogen and progesterone responsible for the growth of uterine fibroids and endometriotic tissues, thereby easing the associated symptoms.

Generic Myfembree from Canada

Canada Drugs Online is proud to serve you the brand Myfembree (Available Soon) from Canada manufactured by Pfizer. The generic form of this medication is currently not available. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Women's health medications such as Addyi and Norlutate.

Myfembree Side Effects:

Common mild side effects of this medication include hot flashes, increased sweating, night sweats, menstrual period changes, hair thinning, and hair loss. If any of these effects persist or worsen, promptly inform your doctor.

Possible serious side effects of this medication include elevated blood pressure, breast lumps, new or worsening depression, anxiety, unusual changes in behavior, persistent nausea or vomiting, loss of appetite, abdominal pain, yellowing of the eyes, dark urine, continuous spotting, sudden heavy bleeding, increased thirst or urination, shortness of breath or rapid breathing, chest, jaw, or left arm pain, unusual sweating, confusion, sudden dizziness or fainting, pain, swelling, and warmth in the groin or calf, sudden and severe headaches, trouble speaking, weakness on one side of the body, sudden vision changes, severe body itching, and rash, swelling of your face, lips, tongue, or throat, difficulty breathing, and dizziness. Stop this medication and seek immediate medical attention if you notice these severe side effects. Also, inform your doctor about any other side effects you notice that are not listed here.

Myfembree has been demonstrated in clinical trials to be safe and effective for the treatment of uterine fibroids and endometriosis. The combination of Relugolix with other active ingredients, such as estradiol and norethindrone acetate, ensures the reduction of adverse effects associated with reduced levels of reproductive hormones (such as osteoporosis) to the barest minimum. The half-life of Myfembree can vary based on its individual components. Relugolix, one of the active ingredients, has a half-life of approximately 25 to 30 hours. Estradiol and norethindrone acetate, the other components, have half-lives of about 1-2 hours and 9-11 hours, respectively.

Myfembree Directions:

This medication is available in tablet form and is typically taken orally, with or without food. Your doctor will determine the best dose for you based on your condition. It is recommended to start using it as early as possible after the onset of menses, but no later than 7 days after menses have started. It is important to take the medication at the same time each day to maintain a consistent level of the drug in the body. Ensure you carefully read the medication guide for more details about its use. Do not use this medication longer than prescribed by your doctor, as it can increase the risk of adverse effects such as osteoporosis. Store at room temperature, away from light and moisture. Keep this medication away from children and pets.

Myfembree Precautions:

Before taking this medication, make sure to inform your doctor about any past or current personal or family history of medical conditions, especially the following:
• Allergic reactions to relugolix, estradiol, and norethindrone acetate, other ingredients of Myfembree, or any other medications;
• Blood clot diseases like deep venous thrombosis;
• Bone problems such as osteoporosis;
• Cancers, especially breast or endometrial cancer;
• Diabetes;
• Eye problems;
• Family or personal history of angioedema;
• Gallbladder disease;
• Heart disease, high blood pressure;
• High levels of cholesterol in the blood;
• Kidney or liver disease;
• Migraine headaches;
• Mental or mood disorders, depression;
• Over 35 years with a history of smoking;
• Stroke;
• Thyroid problems;
• Unexplained vaginal bleeding

While taking this medication, avoid smoking and alcohol, as these substances can heighten the risk of blood clots, stroke, and heart attacks. Myfembree can increase your skin's sensitivity to the sun, potentially increasing the likelihood of sunburn or skin rash. Therefore, it is advisable to take appropriate precautions when exposed to sunlight, including wearing protective clothing and applying sunscreen. Inform your doctor that you are taking this medication before undergoing surgeries, as Myfembree must be stopped for a time before surgery, as it can increase the risk of blood clots. Myfembree is not recommended for use during pregnancy. It is recommended to do a pregnancy test before starting this medication to prevent mistakenly exposing the fetus to Myfembree. Also, ensure you use a reliable birth control method to prevent getting pregnant while taking this medication. However, do not take hormonal birth control pills as they can increase the risk of side effects of Myfembree. Myfembree is also not recommended for use in breastfeeding women. Some medications can interact with Myfembree, increasing the risk of adverse effects. Some of these medications include:
• Antibiotics such as erythromycin;
• Anticonvulsants such as carbamazepine, phenytoin;
• Aromatase inhibitors such as anastrozole, exemestane, letrozole;
• Chronic hepatitis C medications such as ombitasvir, paritaprevir, ritonavir, or dasabuvir;
• Hormonal contraceptives;
• Tamoxifen;
• Tranexamic acid

Therefore, it's important to inform your doctor about all medications, supplements, and herbal remedies you're using before starting Myfembree.