Rifamate (Rifampin/Isoniazid)

Rifamate Information:

Buy Rifamate

Rifamate (Rifampin/Isoniazid) is used to treat tuberculosis infection (TB). It is typically prescribed after the patient's initial use of the individual active ingredients has been proven effective and the dose of each active ingredient has been titrated to a fixed effective dose. It contains two antimicrobial agents as its active ingredients: rifampin and isoniazid. Rifampin inhibits bacterial RNA synthesis by binding to the RNA polymerase enzyme, killing TB bacteria. In contrast, isoniazid inhibits the synthesis of mycolic acids, essential for the bacterial cell wall, leading to bacterial death.

Generic Rifamate from Canada

Canada Drugs Online proudly serves you the brand Rifamate also called Rifinah from the United Kingdom manufactured by Sanofi Aventis. The generic Rifamate is currently not available. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Anti-Infective/Antibiotic medications such as Duricef and Flagyl.

Rifamate Side Effects:

Common mild side effects of this medication include red-orange coloration of tears, sweat, saliva, urine, or stools, numbness, tingling, itching, mild rash, drowsiness, dizziness, headache, muscle pain or weakness, heartburn, gas, diarrhea, and mouth pain. Your doctor may have you take other medications and supplements, such as vitamin B6, while you are taking this medication to help mitigate some mild side effects. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include nausea, upper stomach pain, feeling weak or tired, loss of appetite, dark urine, clay-colored stools, jaundice, vision changes, confusion, hallucinations, unusual thoughts or behavior, fever, unusual weakness, pale skin, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin, severe body itching and rash, swelling of your face, lips, tongue, or throat, difficulty in breathing and extreme dizziness. Stop using this device and seek immediate medical attention if you notice these severe side effects. Also, inform your doctor about other side effects you see that are not listed here.

Clinical studies have shown that Rifamate effectively treats tuberculosis infection, as a combination therapy. It effectively reduces bacterial load and prevents drug resistance. While generally well tolerated by most individuals, it carries risks of adverse effects such as hepatotoxicity, and neurotoxicity. Clinical studies emphasize the importance of regular liver function monitoring and adherence to prescribed dosages to maximize safety and efficacy.

Rifamate Directions:

Take this Rifamate tablets orally on an empty stomach at least 1 hour before or 2 hours after a meal. Consult your doctor for the appropriate dose for you, as it may depend on your age and weight. Check out the leaflet in the medication pack for more details on usage. Take this medication at the same time every day for optimal effectiveness. Do not take more than the prescribed dose of this medication at once. Store at room temperature away from moisture, heat, and light.

Rifamate Precautions:

Before taking this medication, it is essential to inform your doctor about any previous or current medical conditions you may have, especially the following:
• Allergic reaction to rifampin, isoniazid, other ingredients of Rifamate, or any other medication;
• Diabetes;
• HIV infection;
• Kidney disease;
• Liver disease;
• Peripheral neuropathy;
• Porphyria

Your doctor will perform blood tests before and after starting this medication to make sure you do not have conditions that would prevent you from safely using Rifamate and also to monitor the effects of this medication in your body. Avoid the intake of alcohol and alcoholic beverages while taking this medication, as it may increase the risk of liver disease. Also, avoid the intake of foods containing tyramine/histamine, such as cheese and red wine, while taking this medication, as they can cause side effects. Inform your healthcare provider that you take this medication before getting vaccines or immunizations. Consult your doctor before using this medication during pregnancy or while breastfeeding. This medicine is not recommended for use in children younger than 15 years. Some other medications may interact with rifampin and isoniazid, leading to an increase in the risk of developing side effects. Some of these medications include:
• Cobimetinib;
• Conivaptan;
• Eliglustat;
• Flibanserin;
• Lomitapide;
• Voclosporin

Therefore, before using this medication, inform your doctor about any other medications you are currently taking, including herbal medicines and supplements, to determine if it is safe along with Rifamate.