Divigel (Estradiol)

Divigel Information:

Buy Divigel

Divigel (Estradiol) is used to treat symptoms of menopause, such as hot flashes, vaginal dryness, and irritation. It is usually used with progestin drugs in women with an intact uterus undergoing menopause. Divigel contains estradiol as its active ingredient. Estradiol is a form of estrogen hormone. It belongs to the class of drugs known as hormone replacement therapy (HRT). It works by supplementing the body's declining levels of estrogen during menopause, helping to reduce menopausal symptoms and improve the overall quality of life for menopausal women.

Generic Divigel from Canada

Canada Drugs Online is proud to serve you the brand Divigel Single-Dose Gel Packets from Canada manufactured by Searchlight Pharma. The generic Divigel is currently not available. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Menopausal Hormone Therapies such as Osphena and Premarin.

Divigel Side Effects:

Common mild side effects of this medication include mild nausea and vomiting, bloating, breast pain or tenderness, headache, abdominal pain, or weight changes. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include persistent nausea and vomiting, mental or mood changes, breast lumps, unusual vaginal bleeding such as spotting, breakthrough bleeding, and prolonged or recurrent bleeding, increased or new vaginal irritation, itching, odor, or discharge, severe abdominal pain, yellowness of the eyes or skin, dark urine, swelling of hands, ankles, and feet, increased thirst and urination, chest, jaw, or left arm pain, unusual sweating, sudden or severe headache, weakness on one side of the body, confusion, trouble speaking, sudden vision changes such as partial or complete blindness, pain, redness, or swelling of legs, tingling, weakness, or numbness in the arms and legs, trouble breathing, coughing up blood, sudden dizziness and fainting, severe body itching, rash, swelling of your face, lips, tongue, or throat, difficulty in breathing, and dizziness. Discontinue this medication and seek immediate medical attention if you observe these severe side effects. Additionally, inform your doctor about any other side effects not listed here.

Divigel, like other hormone replacement therapies, can be effective in alleviating menopausal symptoms such as hot flashes and vaginal dryness, as proven in various clinical trials. It is also generally well tolerated, with no statistically significant adverse risks compared to placebo. However, its safety should be carefully considered, especially in patients with comorbidities, as hormone therapy may be associated with certain risks, including an increased risk of blood clots, stroke, and breast cancer. It's essential to discuss the potential benefits and risks with a healthcare professional before starting Divigel or any hormone replacement therapy. Estradiol has a half-life of about 13 to 20 hours when administered through transdermal routes.

Divigel Directions:

Divigel is available in the form of a transdermal gel, which should be applied to the skin of the upper thigh, as directed by your doctor. It is generally recommended that this medication be used at the lowest effective dose and for the shortest amount of time possible. You may need to rotate between the right and left upper thigh each day to avoid skin irritation. Do not apply the gel to the breasts, face, vagina, or to irritated or damaged skin. Use this medication regularly as directed by your doctor for optimal effects. Check the leaflet in the medication pack for more usage instructions. Store this medication at room temperature and keep it out of the reach of children.

Divigel Precautions:

Before using this medication, ensure that you inform your doctor about any prior or current medical conditions, including the following:
• Allergic reaction to estradiol, other ingredients of Divigel, or any other medication;
• Asthma;
• Blood clotting or bleeding disorders;
• Bone diseases such as osteoporosis;
• Cancers such as breast cancer, endometrial cancer, ovarian cancer;
• Dementia;
• Diabetes;
• Endometriosis;
• Fibroid;
• Gallstones;
• Heart diseases, high blood pressure;
• High blood cholesterol levels;
• Kidney disease or liver disease;
• Migraines;
• Seizure disorders;
• Stoke;
• Thyroid problems;
• Unexplained vaginal bleeding

This medication should not be used during pregnancy or while breastfeeding. It should also not be used in children. Inform your physician if you are having surgery because this medication might need to be stopped to prevent the development of blood clots during prolonged bed rest from surgery. This medication contains alcohol, making it flammable. Therefore, avoid fire, flame, or smoking until the gel has dried. Also, avoid smoking while using this medication. Estradiol can interact with various other medications, thereby increasing the risk of developing side effects. Some of these other medications include:
• Antifungals such as itraconazole, ketoconazole, voriconazole;
• Bosentan;
• Carbamazepine;
• Celecoxib;
• Ceritinib

Therefore, before using this medication, inform your doctor about any other medications you are currently taking including other topical medicines to determine if it is safe to use along with Divigel.