Silvadene (Silver Sulfadiazene)

Silvadene Information:

Buy Silvadene

Silvadene (Silver Sulfadiazene) is used to prevent and treat wound infections in patients with second to third-degree burns. Its active ingredients are silver and sulfadiazine, which belong to the class of drugs known as topical antimicrobial agents. Silvadene works as an antimicrobial agent by disrupting bacterial cell membranes, interfering with their metabolic processes, and inhibiting their growth. This action helps to prevent and treat bacterial infections in burn wounds.

Generic Silvadene from Canada

Canada Drugs Online is proud to serve you the brand Silvadene from Canada also called Flamazine manufactured by Smith & Nephew. The generic Silvadene (Silver Sulfadiazene) is currently not available. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Dermatology Medications such as Cibinqo and Sodium Sulfacetamide.

Silvadene Side Effects:

Common mild side effects of this medication include pain, burning, or itching of the treated skin, and a change in the color of the skin and mucous membranes (such as the gums) to blue/gray. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include persistent sore throat, fever, chills, easy bruising or bleeding, unusual tiredness or weakness, rapid breathing, fast heartbeat, change in the amount of urine, pink or bloody urine, persistent nausea and vomiting, abdominal pain, dark urine, yellowness of the eyes and skin, mental or mood changes, severe body rash, itching, swelling of the face, tongue, throat, and difficulty in breathing. Discontinue this medication and seek immediate medical attention if you observe these severe side effects. Additionally, inform your doctor about any other side effects not listed here.

Studies have shown that silver sulfadiazine appears to be an effective and safe alternative to antibiotics in the prevention and management of wound infections following burns injury, and the use of this medication helps to decrease length-of-stay in the hospital due to its potent prevention of wound infections in burns patients. It is generally safe to use and well tolerated as it is minimally absorbed in the body. The half-life of silver sulfadiazine ranges from approximately 3 to 5 days.

Silvadene Directions:

Silvadene cream is for use on the affected skin only and is best applied by a trained healthcare professional because it needs to be applied with sterile equipment and minimal trauma to the skin tissue. It is usually applied once every 12 hours to the burns area. Your doctor will determine the appropriate duration and frequency of application of this medication depending on the aim of treatment. However, treatment with this medication is usually continued until the burn site heals or until it is ready for grafting. Check the leaflet in the medication pack for usage instructions. Store at room temperature and keep it away from children and pets.

Silvadene Precautions:

Before applying this topical medicine, it is highly important to inform your doctor of any medical condition you previously or currently have, especially:
• Allergic reaction to silver, sulfadiazine, other ingredients of Silvadene, or any other medication;
• Glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency);
• Kidney disease;
• Liver disease;
• Low white blood cell count

This medication should be used with caution in pregnant women. It should not be used in pregnant women who are close to term or expected date of delivery as it can harm the unborn fetus. Breastfeeding is not recommended while using this medication as it can harm the infant. Do not apply this medication in children younger than 2 months. Certain medications can interact with Silvadene, potentially increasing the risk of side effects. Some of these medications include:
• Allogeneic cultured keratinocytes;
• Products containing collagenase, papain, trypsin;
• Skin products containing sodium sulfacetamide

Therefore, it is crucial to discuss with your doctor all current medications you are taking, including other topical medicine, to determine potential interactions with Silvadene.