Norpramin (Desipramine)

Norpramin Information:

Norpramin (generic name - Desipramine) is a drug used to treat depression. It helps to elevate mood and improve appetite, energy level, and other symptoms of depression. Norpramin belongs to the class of medications called tricyclic antidepressants. It works in the body by preventing the reabsorption of substances in the brain called norepinephrine and serotonin. This increases the level of norepinephrine and serotonin in the body, which helps improve mood and other symptoms of depression.

Generic Norpramin from Canada

Canada Drugs Online is proud to serve you the generic form of Norpramin (Desipramine) from Canada. The brand version is not available. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Antidepressant drugs such as Lexapro and Brintellix.

Norpramin Side Effects:

Common side effects of Norpramin include nausea, vomiting, drowsiness, dizziness, dry mouth, blurry vision, trouble urinating, constipation, loss of appetite, sexual problems, such as decreased libido, or erectile dysfunction, fast heart rate, high blood pressure, and postural hypotension. If you notice these side effects while taking Norpramin and it doesn't go away within a few days, inform your doctor.

While Norpramin is effective in treating depression, it has also been known to worsen the symptoms of depression and increase suicidal thoughts and behaviors on rare occasions. It usually occurs in individuals younger than 25 years. Call your doctor immediately and seek urgent medical attention if you notice any unusual changes in behavior while using Norpramin, such as having thoughts of suicide, panic attacks, trouble sleeping, feeling anxious, agitated, or restless, feeling irritable, hostile, or aggressive, acting on dangerous impulses, or having extreme mood swings.

Other serious side effects associated with the use of Desipramine include skin rash, itching, trouble breathing, swelling of your face, throat, or tongue, eye problems, abnormal awareness of heartbeat, irregular heartbeat, chest pain, shortness of breath, weakness in one part or side of your body, slurred speech, seizures, fever, sweating, muscle stiffness, muscle spasms, agitation, hallucinations, tremors, high or low blood pressure, and loss of consciousness. Seek immediate medical attention if you notice any serious side effects or others not listed here that worry you.

Norpramin Directions:

The right dose depends on factors such as age, the severity of your condition, other coexisting medical conditions, and how you react to the first dose. Therefore it is imperative to use the drug as instructed by your doctor to avoid the risk of side effects. However, the recommended dose for adults is 100–200 mg daily, which can be split into two and taken twice a day, 12 hrs apart. For children between 13-17 years and elderly individuals >65 years, the recommended dose is 25-50 mg daily. Take this medication by mouth with or without food. If you take the medication once daily, take it at nighttime, before you sleep. Take this medication regularly to get the desired results. If you miss a dose, take it as soon as possible unless it's almost time for the next dose. Do not use more than the prescribed dose to make up for a missed one. Please do not stop this medication abruptly, as it can cause withdrawal symptoms. Consult your doctor on how to stop taking this drug gradually. Store this medication at room temperature and keep it away from light and moisture and out of children's reach.

Norpramin Precautions:

Inform your doctor about any medical conditions you may have, as these conditions might increase the risk of developing serious side effects. Certain medical conditions are necessary to discuss with your doctor before using this drug. These include:
• Bipolar disorder or mania;
• Breathing problems such as asthma;
• Diabetes;
• Eating disorders such as bulimia;
• Eye problems such as glaucoma;
• Heart problems;
• Hyperthyroidism (high thyroid levels);
• Kidney disease;
• Liver disease;
• Seizure disorders such as epilepsy;
• Urination problems.

Inform your doctor about any history of allergic reactions to any medication. Do not take this medication if you are allergic to Norpramin or its ingredients. Avoid taking alcohol as it can interfere with the action of Norpramin and potentiate its side effects. Inform your doctor if you currently smoke or have just stopped smoking. Avoid smoking cigarettes while taking this drug, as it can affect its concentration in the blood. Do not drive, use machinery, or do anything that needs alertness or clear vision until you are sure safely. Norpramin should not be used in pregnancy or while breastfeeding unless your doctor has assessed its benefits and risk for these situations. Do not use Norpramin in children less than 13 years of age. Desipramine can make your skin more sensitive to sunlight, so wear protective clothing and avoid exposure of your skin to sunlight. It might take about 2-3 weeks before you start to see the effects of Norpramin. However, if your symptoms don't improve or worsen after using Norpramin for that period, contact your doctor. Consult your doctor regularly while using this drug as regular laboratory and other medical tests must be carried out routinely to prevent or detect side effects early.

Certain drugs are known to interact with Norpramin, subsequently either potentiating its side effects or preventing it from working properly. Some of these medications include:
• Cimetidine;
• Flecainide;
• Monoamine oxidase inhibitors (MAOIs) such as isocarboxazid;
• Olanzapine;
• Other Antidepressants such as duloxetine;
• Phenobarbital

It is important to discuss with your doctor any medication you are currently taking, including herbal medications and supplements, to find out if it can interact with Norpramin.