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Cetrotide Injection SC (Cetrorelix Acetate)

Type: drug type
Product: Cetrotide Injection SC Vial (Local Pickup Only)
Manufacturer: Serono
Country: Canada
Dosage: 250 mcg
Qty: 1
USD $147.99

Cetrotide Injection SC Information:

Cetrotide (cetrorelix acetate for injection) is a synthetic decapeptide with gonadotropinreleasing hormone (GnRH) antagonistic activity. Cetrotide (cetrorelix acetate for injection) is indicated for the inhibition of premature LH surges in women undergoing controlled ovarian stimulation. Ovarian stimulation therapy with gonadotropins (FSH, HMG) is started on cycle Day 2 or 3. The dose of gonadotropins should be adjusted according to individual response. CetrotideTM (cetrorelix acetate for injection) may be administered subcutaneously either once daily (0.25 mg dose) or once (3 mg dose) during the early- to mid-follicular phase. In the single dose regimen, 3 mg of Cetrotideä is administered when the serum estradiol level is indicative of an appropriate stimulation response, usually on stimulation day 7 (range day 5-9). If hCG has not been administered within four days after injection of Cetrotide 3 mg, CetrotideT0.25 mg should be administered once daily until the day of hCG administration. In the multiple dose regimen, 0.25 mg of Cetrotideä is administered on either stimulation day 5 (morning or evening) or day 6 (morning) and continued daily until the day of hCG administration. When assessment by ultrasound shows a sufficient number of follicles of adequate size, hCG is administered to induce ovulation and final maturation of the oocytes. No hCG should be administered if the ovaries show an excessive response to the treatment with gonadotropins to reduce the chance of developing ovarian hyperstimulation syndrome (OHSS). Administration CetrotideT 0.25 mg and 3 mg can be administered by the patient herself after appropriate instructions by her doctor. Directions for using CetrotideT 0.25 mg and 3 mg: 1. Wash hands thoroughly with soap and water. 2. Flip off the plastic cover of the vial and wipe the aluminum ring and the rubber stopper with an alcohol swab. 3. Put the injection needle with the yellow mark (20 gauge) on the pre-filled syringe. 4. Push the needle through the rubber stopper of the vial and slowly inject the solvent into the vial. 5. Leaving the syringe on the vial, gently agitate the vial until the solution is clear and without residues. Avoid forming bubbles. 6. Draw the total contents of the vial into the syringe. If necessary, invert the vial and pull back the needle as far as needed to withdraw the entire contents of the vial. 7. Replace the needle with the yellow mark by the injection needle with the grey mark (27 gauge). 8. Invert the syringe and push the plunger until all air bubbles have been expelled. 9. Choose an injection site at the lower abdominal wall, preferably around the navel. If you are on a multiple dose (0.25 mg) regimen, choose a different injection site each day to minimize local irritation. Use the second alcohol swab to clean the skin at the injection site. Gently pinch up the skin surrounding the site of injection. 10. Insert the needle completely into the skin at an angle of about 45 degrees. 11. Once you have inserted the needle completely, release your grasp of the skin. 12. Gently pull back the plunger of the syringe to check the correct positioning of the needle. · If no blood appears, inject the entire solution by slowly pushing the plunger. Thereafter, withdraw the needle and gently press the alcohol swab on the injection site. · If blood appears, withdraw the needle with the syringe and gently press the alcohol swab on the injection site. Discard the syringe and the drug vial. Use a new pack and repeat the procedure. 13. Use the syringe and needles only once. Dispose of the syringe and needles properly after use. If available, use a medical waste container for disposal.

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