Sinemet CR (Carbidopa/Levodopa)

Sinemet CR Information:

Sinemet CR (generic name Carbidopa/Levodopa) is a medication for treatment of symptoms of Parkinson’s disease. This medication is a combination of levodopa and carbidopa in a controlled release tablet. The symptoms of Parkinson’s disease are caused due to lack of dopamine, a naturally occurring chemical produced by the brain. Dopamine is involved in conducting messages in certain regions of brain that control muscle movement. In Parkinson’s disease, difficulty in movement occurs due to too little production of dopamine. Levodopa acts by replenishing the dopamine in brain and carbidopa ensures that enough levodopa reaches the brain where it is needed. Parkinson’s disease is a chronic disorder characterized by slow and unsteady movement, muscle stiffness and tremors, causing difficulty in performing normal daily activities. If you are diagnosed with any of the symptoms, your doctor will discuss the most effective treatment for your particular condition.

Generic Sinemet CR from Canada

Canada Drugs Online is proud to serve you brand and generic Sinemet CR from Canada manufactured by Bristol-Myers Squibb and a different manufacturer. Please call our toll free at 1-877-900-3784 for details. We also carry the brand Sinemet CR from United Kingdom manufactured by Merck and the generic Carbidopa/Leovdopa from India by a different manufacturer.

CanadaDrugsOnline.com also carries other Parkinson’s disease medications and Canadian drugs such as Azilect and Dostinex.

Sinemet CR Side Effects:

As with any drug, there may be side effects from taking Sinemet CR. Some of the common side effects of Sinemet CR include abnormal movements (which may or may not resemble your Parkinson’s symptoms), nausea, hallucinations, confusion, dizziness, light-headedness, drowsiness and dry mouth. Other possible side effects include abnormal dreams, difficulty sleeping, mental changes, depression, weakness, vomiting, loss of appetite, flushing, irregular heartbeat, dark color in saliva, urine and sweat and hair loss. If you experience any side effects (including the ones not listed here), stop taking the medication and seek medical attention immediately.

Sinemet CR Directions

You should follow the instructions of the doctor who prescribed Sinemet CR to you. Directions and dosage information can also be found on the pack or leaflet inside the pack. Brand Sinemet CR comes as controlled release tablet in the dosage form of 50 mg/200 mg. The generic equivalent of Sinemet CR also comes in the dosage form of 25 mg/100 mg and 50 mg/200 mg. The usual dose prescribed by the doctor is variable, adjusted according to the severity of your disease and your response to the treatment. Never change the dose of Sinemet CR unless your doctor tells you to. Swallow the tablets whole with a glass of water. Do not chew the tablets. Sinemet CR should be stored at room temperature of 15°C to 30°C, in a closed container, protected from light and moisture. It should be kept out of the reach and sight of children.

Sinemet CR Precautions

If you are allergic to any of the ingredients of Sinemet CR, you should avoid taking it and inform your doctor. You should also not take Sinemet CR and consult your doctor, if you have any suspicious skin lesions (moles) which have not been examined by your doctor, ever had skin cancer, are being treated with certain MAO inhibitor drugs within the last 2 weeks, have narrow angle glaucoma, have untreated heart, liver, kidney, lung, blood hormonal disease or have been told that you should not take sympathomimetic drugs such as isoproterenol, epinephrine. You must consult also your doctor if you have any medical conditions including allergies, depression, mental disturbances, lung, kidney, heart or hormonal problems, skin cancer, suspicious skin lesions, ulcer in your gut, suffer from seizures, glaucoma, have been previously treated with levodopa, are pregnant or planning to become pregnant, are breastfeeding, are going to have an operation that needs general anesthesia, drive or operate machinery. You must consult your doctor if you are taking any other medications as they may interact with Sinemet CR, including antihypertensive drugs, some medications used to treat psychiatric conditions or mental depression (including phenothiazines, butyrophenones, risperidone, selegiline, tricyclic antidepressants and monoamine oxidase inhibitors), tetrabenazine (medications used to treat Huntington’s Disease), phenytoin, papaverine, isoniazid, metoclopramide, iron salts (such as multivitamins). You feel sleepy, drowsy, or, rarely, may suddenly fall asleep without warning (i.e. without feeling sleepy or drowsy) when taking Sinemet CR. During treatment with Sinemet CR, take special care when you drive or operate a machine. If you experience excessive drowsiness or a sudden sleep onset episode, refrain from driving and operating machines, and contact your physician. Recommended dosage Your doctor will tailor your individual dosage carefully, depending on your response to previous therapy and symptoms. ADULTS: For patients with mild to moderate symptoms, the initial recommended dose is 1 tablet of Sinemet CR taken 2 times a day. Starting doses should be spaced out every 4 to 8 hours and then adjusted to each patient's individual response. The usual long-term dose is 2 to 8 tablets per day, taken in divided doses every 4 to 8 hours during the waking day. Higher doses (12 or more tablets per day) and shorter intervals (less than 4 hours) have been used, but are not usually recommended. When doses of SINEMET CR (levodopa/carbidopa) are given at intervals of less than 4 hours, and/or if the divided doses are not equal, it is recommended that the smaller doses be given at the end of the day. An interval of at least 3 days between dosage adjustments is recommended. Dosage adjustment of SINEMET CR (levodopa/carbidopa) may be necessary if your doctor prescribes additional medications.