Prograf (Tacrolimus Immediate Release)

Prograf Information:

Buy Prograf

Prograf (Tacrolimus Immediate Release) is an immunosuppressive medication used in combination with other medications, such as azathioprine or mycophenolate mofetil, to prevent organ rejection in transplant recipients. It is also used in treating rheumatoid arthritis when other forms of treatment have failed. Its active ingredient is tacrolimus, and it belongs to the class of drugs known as calcineurin inhibitors. Prograf works by inhibiting calcineurin, a protein involved in the immune system response, thereby suppressing the immune system's activity and reducing the risk of organ rejection after transplantation.

Generic Prograf from Canada

Canada Drugs Online is proud to serve you the brand Prograf Canada and Turkey manufactured by Astellas Pharma. The generic Tacrolimus Immediate Release comes from India also called Pangraf by Panacea Biotec and Tacrograf by Biocon Pharma and from Canada by a different manufacturer. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Immunosuppressive Agents such as Cortef and Florinef.

Prograf Side Effects:

Common mild side effects of this medication include shaking, headache, diarrhea, mild nausea and vomiting, stomach discomfort, loss of appetite, trouble sleeping, and numbness or tingling of the hands and feet. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include mental or mood changes, abnormal reduction or increase in the amount of urine, pounding heartbeat, shortness of breath, swelling ankles or feet, unusual tiredness, unusual or sudden weight gain, hearing loss, ringing in the ears, pain, redness or swelling of arms or legs, easy bruising and bleeding, muscle pain, cramp or weakness, persistent nausea and vomiting, yellowness of the eyes and skin, dark urine, severe abdominal pain, severe leg pain, confusion, difficulty concentrating, difficulty moving your muscles, problems with speech, seizure, vision changes, loss of consciousness, high blood pressure, increased thirst and hunger, frequent urination, severe body itching and rash, swelling of your face, lips, tongue, or throat, difficulty in breathing, and dizziness. Stop this medication and seek immediate medical attention if you notice these severe side effects. Also, inform your doctor about any other side effects you notice that are not listed here.

The safety and efficacy of Prograf (Tacrolimus) have been well-established through extensive clinical studies and real-world use. It is considered a highly effective immunosuppressive medication for preventing organ rejection in transplant recipients, with minimal but rare side effects, especially when used under the close supervision of a qualified medical practitioner. It has also been shown to be safe and effective in treating rheumatoid arthritis and slowing the progression of the disease. It has an average half-life of 12 hours.

Prograf Directions:

Prograf is available in the form of an immediate-release capsule, which should be taken orally with or without food as directed by your doctor. Your doctor will determine the best dose for you depending on your medical condition and response to treatment. It is important to use this medication regularly as directed by your doctor for optimal effect. Swallow this medication whole and avoid chewing or crushing it. Avoid the intake of grapefruit or grapefruit juice while taking this medication. Refer to the leaflet in the medication pack for more usage instructions. Store this medication in a cool and dry place, protect it from light and moisture, and keep it out of the reach of children.

Prograf Precautions:

Before taking this medication, ensure you inform your doctor about any past or current personal or family history of medical conditions, especially the following:
• Allergic reaction to Tacrolimus, other ingredients of Prograf, or any other medication;
• Cancer;
• Current infections;
• Diabetes;
• Electrolyte imbalances such as high levels of potassium;
• Heart disease;
• High blood pressure;
• Kidney disease;
• Liver disease;
• Reversible posterior leukoencephalopathy syndrome (RPLS)

Limit the exposure of your skin to sunlight and wear sunscreen and protective clothing outdoors, as this medication can make your skin more sensitive to the sun. This medication can cause drowsiness or otherwise, so avoid driving, operating machinery, or performing other potentially hazardous tasks until you have know how it affects you. Also, avoid close contact with anyone who has an infection that may easily spread, such as chickenpox, COVID-19, measles, flu. Before having a vaccine, inform your healthcare provider that you are taking this medication. This medication should not be used in pregnant or breastfeeding women. Inform your doctor if you become pregnant while using this medication. Some medications may interact with Tacrolimus, affecting the way it works in the body. Such medications include:
• Amphotericin B deoxycholate;
• Cidofovir;
• Elagolix;
• Fluconazole;
• Lefamulin;
• Mifepristone;
• Neomycin;
• Saquinavir;
• Thioridazine

Therefore, make sure you inform your doctor about all the medications, including herbal medications and supplements you are taking before starting Prograf to prevent drug interactions.