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What other drugs will affect Zoloft?

If you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) during the last 2 weeks then it is recommended not to take Zoloft.

If you are taking pimozide (Orap) then do not take Zoloft. A dangerous drug interaction could result
It is recommended that before using Zoloft tell your doctor if you are taking

- benzodiazepine such as diazepam (Valium), alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), temazepam (Restoril), triazolam (Halcion), and others;
- cimetidine (Tagamet, Tagamet HB);
- phenothiazine including chlorpromazine (Thorazine), thioridazine (Mellaril), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), and others;
- digoxin (Lanoxin);
- tricyclic antidepressant such as amitriptyline (Elavil), imipramine (Tofranil), doxepin (Sinequan), nortriptyline (Pamelor), and others;
- lithium (Lithobid, Eskalith, others) or clozapine (Clozaril);
- bupropion (Wellbutrin, Zyban).
- almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig);If you are taking any of the medicines listed above then you may not be able to take Zoloft, or you may require a dosage adjustment or special monitoring during treatment.

If you are taking disulfiram (Antabuse), it is advised not to take the Zoloft Oral Concentrate. The oral solution contains alcohol, which may interact with disulfiram.



Zoloft is used to treat depression, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), social anxiety disorder (social phobia), and a severe form of premenstrual syndrome called premenstrual dysphoric disorder (PMDD); this medicine is a selective serotonin reuptake inhibitor (SSRI).The balance of certain natural substances in the brain (neurotransmitters) is restored with the
Zoloft Articles
Why is Zoloft prescribed?
What should you discuss with your healthcare provider before taking Zoloft?
Managing your condition
What other drugs will affect Zoloft?
What should you watch for while taking Zoloft?

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