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Premarin
Common Uses |
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Tablets
CONJUGATED ESTROGENS (ESS-troe-jenz) is the chemical name
for Premarin.
Premarin Common Uses
Premarin is used to reduce menopause symptoms (such as
vaginal dryness); this medicine is a female hormone and
is usually given to women who do not produce the proper
amount. It can also be used in other circumstances for
treatment, as if determined by your doctor.
Before Using Premarin
Warning: The chances of womb (endometrial) cancer (especially
in women who receive estrogen-only hormone therapy) are
increased to whom Estrogens have been reported. The risk
of cancer of the ovary is also increased by Estrogens.
To prevent heart disease or dementia, it is recommended
not to use Estrogen-containing products. The risk of heart
disease (including heart attacks), stroke, serious blood
clots in the lung (pulmonary embolism) or leg (deep venous
thrombosis), cancer of the breast, or dementia may be
increased if Estrogen is taken alone or in combination
with another hormone (progestin). The risk of this medicine
depends on the time period of your doses or on the amount
of the doses you are taking in your schedule. It will
be beneficial for you if you take this medicine for a
short-term time at the lowest effective dose because it
will minimize the chance of serious side effects which
you can have if you take it for long-term period. For
more details, contact your doctor/pharmacist. There are
chances that any other medicines or medical conditions
may interact with this medicine therefore all prescription
and over-the-counter medicine that you are taking should
be known by your doctor or pharmacist. If you are taking
corticosteroids (such as prednisone), seizure medicines
(such as phenytoin, carbamazepine, or phenobarbital),
"blood thinners" such as warfarin, certain antifungal
medicines (such as ketoconazole or itraconazole), macrolide
antibiotics (such as clarithromycin or erythromycin),
rifampin, ritonavir, cimetidine, or St. John's wort than
additional observation should be required of your dose
or condition. Without consulting your doctor do not start
or stop taking the medicine. If you have any other medical
conditions including any personal or family history of
cancer, breast lumps, womb problems (such as uterine fibroids,
endometriosis, or cancer), heart disease (such as high
blood pressure, heart attacks, congestive heart failure),
stroke, diabetes, cholesterol/lipid problems, gallbladder
disease, low thyroid hormone (hypothyroidism), high blood
pressure during pregnancy (toxemia), yellowing of eyes/skin
(cholestatic jaundice) during pregnancy or with past estrogen
use, depression, asthma, seizures, migraine headaches,
kidney problems, abnormal calcium level in the blood,
lupus, growths on the liver, tobacco use, if you are extremely
overweight or have experienced excessive weight gain,
any allergies, pregnancy, or breast-feeding than immediately
inform your doctor. If you have a history of undiagnosed
or abnormal vaginal bleeding, certain types of cancer,
estrogen-dependent growths, blood clots, liver problems,
certain blood disorders (porphyria), or active/recent
(within the past year) stroke or heart attack, it is recommended
not to use this medicine. If you have any further queries
regarding the medicine than contact your doctor.
Storage
Premarin should be stored at room temperature between
15-30°C (59-86°F) in a tightly-sealed container
and in a dry place and away from heat and direct light.