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Chemical Name: Bortezomib
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Velcade Information:
Velcade (generic name: Bortezomib) is chemotherapy medication for the treatment of multiple myeloma. Mutiple myeloma is also known by the names "plasma cell myeloma" and Kahler’s disease. It is a cancer of the plasma cells, which are a type of white blood cell that is normally responsible for the production of antibodies which fight off diseases and infections. With multiple myeloma, collections of abnormal blood cells collect inside the bones which cause lesions/pits on the bones and inside the bone marrow, where they interfere with normal blood cells. Veclade works by interfering with the growth of certain types of cancerous cells to prevent them from spreading (known as metastasising in terms of cancer) to other parts of the body. Velcade is sometimes prescribed as a “last resort” when other types of cancer medications have been tried with a patient and failed to work effectively or efficiently. Multiple myeloma can often lead to anaemia, and this is usually one of the fist symptoms that cause the myelomato be detected. Other symptoms include kidney dysfunction as well as high erythrocyte sedimentation. These symptoms normally will cause the doctor to request further testing to diagnose the cause. It remains unknown at present what causes multiple myeloma, but it is known that the disease or cancer, is not contagious. People over the age of 65, of African-American origin and who are male are at higher risk statistically than others of contracting multiple myeloma.
Velcade Side Effects:As with any drug, there may be side effects from taking Velcade including mild nausea, vomiting, upset stomach, diarrhea, constipation, headache, blurred vision, dizziness, muscle pain, bone/joint pain, sleep problems, mild rash, itchy skin and skin irritation at the injection site. More serious side effects may include new/worsening nerve problems, feeling light headed or like you might pass out, dry cough, trouble breathing, severe headache, vision problems, confusion, seizures, black/bloody/tarry stools, vomit that looks like coffee grounds, severe constipation, easy bruising or bleeding, fever, chills, body aches, flu-like symptoms, fast/slow heart rate, weak pulse, lower back pain, blood in the urine, urinating less than normal, weak muscles, overactive reflexes, loss of appetite and jaundice (yellowing of the skin and eyes). If you experience any side effects you must seek medical attention immediately for safety.
Velcade Directions: You should follow the instructions of the doctor who prescribed Velcade to you. Directions and dosage information can also be found on the pack or leaflet inside the pack. Velcade is administered as an injection. The injection is done inside the doctor surgery or hospital and cannot be administered at home.
Velcade Precautions: If you are allergic to any of the ingredients of Velcade, you should avoid taking it and inform your doctor. You must consult your doctor if you have any pre-existing medical conditions including diabetes, liver disease, kidney disease, if you are on dialysis, a bleeding or blood clotting disorder, low platelet levels, low white/red blood cells, heart disease, congestive heart failure, herpes, history of shingles, high or low blood pressure and nervous system conditions/problems. You must consult your doctor if you are taking any other medications as they may interact with Velcade, including dexamethasone, rifabutin, St John’s Wort, antibiotics, antifungals, antidepressants, barbiturates, oral diabetic medications, HIV/AIDs medications, narcolepsy medications and seizure medications. It is important that you inform your doctor if you are pregnant, planning to conceive or breastfeeding as Velcademay cause harm to unborn and new born babies. You should avoid people who have colds or flu as Velcade makes you more susceptible to catching contagious viruses.
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