Avandaryl Information:

Avandaryl is a combination of two drugs, Rosiglitazone (Avandia) and Glimepiride (Amaryl). One of the medicines in Avandaryl, rosiglitazone, helps your body use its own natural insulin better. That means it lowers your insulin resistance. The other medicine, glimepiride, helps your body release more insulin. Avandaryl can start lowering your blood sugar in a few days. It may take 2-3 months to see the full effect on your blood sugar level.

Avandaryl Side Effects:

Avandaryl may cause low blood sugar. Lightheadedness, dizziness, shakiness or hunger may mean that your blood sugar is too low. If you have kidney problems, you may need a lower dose of Avandaryl to reduce problems with low blood sugar. Talk to your doctor if low blood sugar is a problem for you. Some people may experience tiredness, weight gain or swelling with Avandaryl. Avandaryl may cause fluid retention or swelling, which could lead to or worsen heart failure, so you should tell your doctor if you have a history of these conditions. If you experience an unusually rapid increase in weight, swelling or shortness of breath while taking Avandaryl, talk to your doctor immediately. In combination with insulin, rosiglitazone, one of the components of Avandaryl, may increase the risk of other heart problems. Avandaryl is not approved for use with insulin. Avandaryl is not recommended for patients with NYHA Class 3 and 4 cardiac status or active liver disease. Blood tests should be used to check for liver problems before starting and while taking Avandaryl. Tell your doctor if you have liver disease, or if you experience unexplained tiredness, stomach problems, dark urine or yellowing of skin while taking Avandaryl. If you are nursing, pregnant or thinking about becoming pregnant, talk to your doctor before taking Avandaryl. Avandaryl may increase your risk of pregnancy. Your doctor should check your eyes regularly. Very rarely, some patients have experienced vision changes due to swelling in the back of the eye while taking rosiglitazone, a component of Avandaryl.